The Dangers Of Mixing Xanax And Nyquil Together

The Dangers Of Mixing Xanax And Nyquil Together

Xanax is a very powerful benzodiazepine that is very habit forming. The strong side effects are what draw people to this drug, whether it is prescribed by a professional psychiatrist or purchased illegally. There are many dangers that one will face, if they choose to mix Xanax and Nyquil together. Of course, this warning will not stop addicts or those that are looking for a “High” to be deterred from this risky behavior.

Extremely Addictive

Xanax is very addictive, even when following the prescribed dosage recommendations. By mixing it with Nyquil, you will be increasing your risk of becoming addicted to this homemade concoction. Many Xanax users will become immune to the drug, after taking for a significant period of time. When this happens, they will be impelled to mix the drug with over the counter cold and flu medications, so they can achieve a bigger “High”.

Severe Withdrawal Symptoms

If you misuse your Xanax prescription, you may find yourself not having enough to last for their entire month. This means that you may risk facing some form of withdrawal, whether it be temporary until you get your next prescription filled or for a longer period of time. If you are forced to suddenly stop taking Xanax, you may find yourself in a life threatening situation.


Combining Xanax and Nyquil will increase the side effects of each drug dramatically. This will also increase your risks of addiction, overdose, and death. If you are currently being prescribed Xanax for anxiety, you should not take any over the counter cold and flu medication, unless prescribed by a physician.

David Warren
David Warren

Pharmaceutical specialist at
David Warren is a pharmaceutical specialist that dispenses prescription medication on a daily basis. He received a Bachelor of Science degree in pharmacy from the University of Tennessee in 1991. With over 50 publications on medication-related and pharmacy topics, David has been able to share his experiences and knowledge with others.

David with lots of experience and knowledge in medications that are utilized to treat a wide range of medical conditions. Before David dispenses a medication to a patient, he will go over the side effects, dosage recommendation and contraindications.
David Warren

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  1. chapparitta July 03, 03:32 Reply
    I've been on 1mg Alprazalom for over 10 years for panic attacks and insomnia​. My new Dr cut me WAY back. From 120 a month to 30 a month. I went days with very little sleep. I ended up in the ER. With Iv meds I was able to come home and sleep. Now it's been 2 nights without sleep, heading to night three. Is it safe to take zzquil, and not my 1 mg Alprazalom?
  2. Dr Pharmacologist February 21, 21:10 Reply
    Actually this information is not accurate. The reason they say you can't take xanax (alprazolam) with cold meds is because SOME cold meds contain antihistamines that are potentially sedating. Combining xanax with any sedative can result in over-sedation and in extreme cases (usually by taking more than the recommended dosage) this over-sedation can suppress breathing and result in death. This is very very rare and it is much more dangerous to mix xanax and alcohol. But many cold meds do not contain sedating antihistamines and in fact contain stimulants such a pseudo ephedrine or phenylephrine. With these types of medication there is almost no risk to combining with xanax and xanax sedating effects will actually be reduced. So for example taking eg pseudofed and xanax together will not cause any problems. Besides most people who take xanax regularly will have significant tolerance to its sedative effects and thus the weak sedating powers of antihistamine cold meds will be virtually nil in comparison to the xanax itself.
  3. Anonymous December 28, 01:40 Reply
    Omg come on ppl can't you also include the facts as well as the addiction parts I just need some relief I'm prescribed Xanax can I take nyquil with it gees not everyday just right now iam sick.
  4. Anonymous December 28, 01:37 Reply
    This is aweful why can't you put the facts on here as well. you mentioned everything else all I want to know is if it is safe to take together once or maybe twice iam sick not enough to pay a out ragious doctor bill but need something to take and iam on Xanax. I not a addict I just need some relief.
  5. Your site sucks December 15, 21:04 Reply
    Worst article I have ever read, embarrassed that 'doctors' run this site. Just pathetic fear mongering without providing any real information or facts.
    • The Team December 16, 06:28 Reply
      We are accustomed to receive negative or aggressive comments in the medication mixing section, especilly this one.This site is for a large public of profane who want access to the informations quickly without reading hundred of pages, If you have a technical question regarding the biochemistry sensibility of the brain feel free to ask, in the meantime I recommend you to do not to mix xanax and nyquil or similar substance.
  6. Cjohn2 September 01, 14:53 Reply
    This had to be the worst information ever. I literally searched can I take nyquil and xanax because i have a cold and im a little anxious (not a drug user, i seldomly take any xanax but i do have an perscription) and i find an article that says dont take xanax and nyquil because i will increase my chances of getting addicted and overdosing?!?! Wtf. I only wanted to know is it safe. I did not ask if i have a raging addictive personality is it a good idea to abuse these.
    • Anonymous September 24, 01:20 Reply
      Same here. I have a kidney stone and bad sinus cold symptoms. I took 1 Xanax that I'm prescribed and trying to see if it's safe as I also took 15mg of loritab total today but not recently
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