How Long Does Oxycodone Stay In Your System

Prescription pain pill addictions are continuously increasing, especially in adolescents and younger adults. Oxycodone is a very powerful opioid that is prescribed for mild to moderate pain. If taken as prescribed by the pain clinic physician, this opioid will effectively manage pain. Below you will discover more about this drug and how long it stays in the system.

What Is Oxycodone?

In basic terms, Oxycodone is an opiate, which is related to codeine. The drug is sometimes referred to as a narcotic. In a medical sense, Oxycodone is used to combat severe and moderate pain. The truth is available in an extended-release formula, which is used to treat pain throughout the day and night. Individuals that suffer from asthma and other breathing problems should not consume Oxycodone.

Oxycodone Duration

Oxycodone will remain in the system for up to 72 hours after the last use. Oxycodone is a very popular prescription narcotic, because it can effectively treat individuals that suffer from pain very safely. Of course, this is not to say that the user will not experience side effects. It is crucial to follow the directions provided by the physician to a tee, in order to avoid overdose and addiction.

Side Effects

Oxycodone causes several different side effects, which range from mild to severe. Side effects include:

  • Abdominal pain
  • Nausea/vomiting
  • Constipation
  • Xerostomia (dry mouth)
  • Drowsiness
  • Headache
  • Dizziness
  • Fatigue

A more severe side effect that can be very dangerous or even fatal at times is respiratory suppression. If you suffer from any type of respiratory disorder, you should definitely advise your physician of this important information. Oxycodone can definitely worsen the symptoms of asthma and COPD. Your physician can always prescribe you a more suitable alternative to combat your pain.

Before Using Oxycodone

There are some risks involved with taking Oxycodone. Although the medication is fairly safe on its own, you should not use it, if you have any preexisting conditions. Below, you will find some of these existing conditions, which may prove to be problematic, when using Oxycodone.

  • Breathing problems or lung disease
  • History of seizures, brain tumors or head injuries
  • Problems urinating
  • Kidney or liver disease
  • Addison’s disease
  • Gallbladder, thyroid or pancreas problems
  • History of addiction, drug abuse or mental illness

If you suffer from any of the problems listed above, you will want to make sure to speak with your medical professional, before consuming Oxycodone.

Oxycodone Half-Life

In order to get a better understanding of this specific drug, it is vital to look at its half-life. According to medical experts, the half-life for Oxycodone hydrochloride tablets is right around 3.5 to 4 hours. Of course, this will vary based on the specific amount of the drug consumed. Obviously increasing the dosage will lead to a longer half-life and vice versa.

Keeping out of Reach of Children

If you have an open door policy at your home, where many children are visiting throughout the day, you should keep your medications out of their reach. Children like to search through cupboards and bathroom cabinets, which are the most common places to store drugs. Oxycodone overdose can occur within a few minutes after consumption, if taken in high doses and these risks are much higher in children. Respiratory distress and fatality is inevitable, if treatment is not rendered immediately.


When it comes down to it, Oxycodone can be a very effective medication for combating pain. Of course, it does come with a minute amount of risks and negative side effects. Before consuming this medication, you should familiarize yourself with all of these, in order to keep yourself safe! Above, you have found this information and it is recommended that you use it to your advantage.

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David Warren
David Warren is a pharmaceutical specialist that dispenses prescription medication on a daily basis. He received a Bachelor of Science degree in pharmacy from the University of Tennessee in 1991. With over 50 publications on medication-related and pharmacy topics, David has been able to share his experiences and knowledge with others. David with lots of experience and knowledge in medications that are utilized to treat a wide range of medical conditions. Before David dispenses a medication to a patient, he will go over the side effects, dosage recommendation and contraindications.